DeCaprio Lab - Merkel Cell Carcinoma, Polyomavirus, Cell Cycle Research
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    • Merkel cell carcinoma
    • The DREAM complex/Cell cycle
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    • ​James A. DeCaprio, MD
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Division of Molecular and Cellular Oncology
Independent Laboratory Investigators
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James DeCaprio, MD
Professor of Medicine, Harvard Medical School
Chief, Division of Molecular and Cellular Oncology, Dana-Farber Cancer Institute
Research Areas: Merkel cell carcinoma, Merkel cell polyomavirus, Cell cycle gene regulation, RB and the DREAM complex

DeCaprio Lab Website
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Andrew Aguirre, MD, PhD
Assistant Professor of Medicine, Harvard Medical School
Associate Member, Broad Institute of MIT and Harvard
Research Areas: Pancreatic Cancer, RAS Biology, Genomics, Cancer Therapeutics
Investigator, 
Hale Family Research Center
Aguirre Lab Website
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David Barbie, MD
Associate Professor of Medicine, Harvard Medical School
Associate Director, Robert and Renée Belfer Center for Applied Cancer Science
Research Areas: Lung Cancer, Targeted Therapy, Innate Immunity
Barbie Lab Website
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Himisha Beltran, MD
Associate Professor of Medicine, Harvard Medical School
Research Areas: Prostate Cancer, Treatment Resistance, Biomarkers, Tumor biology, Precision Medicine
Beltran Lab Website
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Myles Brown, MD
Emil Frei III Professor of Medicine, Harvard Medical School
Director, Center for Functional Cancer Epigenetics
Brown Lab Website


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Matthew Freedman, MD
Professor of Medicine, Harvard Medical School
Center for Cancer Epigenetics
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William Freed-Pastor, MD, PhD
Instructor of Medicine, Harvard Medical School
Research Areas: Pancreatic Cancer, Tumor Immunology, Immunotherapy 
Freed-Pastor Lab Website
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Marios Giannakis, MD, PhD
Assistant Professor of Medicine, Harvard Medical School
Research Areas: Colorectal Cancer, Translational Research, Immunotherapy, Molecular Epidemiology, Wnt-signaling
Giannakis Lab Website


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William Hahn, MD, PhD
Executive Vice President & Chief Operating Officer
William Rosenberg Professor of Medicine, Harvard Medical School
Research Areas: Oncogene Cooperation, Functional Genomics, Synthetic Lethality, Epithelial Transformation
Hahn Lab Website
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Rizwan Haq, MD, PhD
Assistant Professor of Medicine, Harvard Medical School
Haq Lab Website

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Sarah Hill, MD, PhD
Assistant Professor of Pathology, Harvard Medical School
Research Areas: Organoids, Ovarian Cancer, DNA Damage Repair, Immuno-oncology, Replication Stress
Hill Lab Website
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Megan Insco, MD, PhD​
Instructor of Medicine, Harvard Medical School
Research Areas: Melanoma, RNA Quality Control, Transcription, Novel Therapeutics, Zebrafish Animal Modeling
Insco Lab Website
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Pasi A. Jänne, MD, PhD
Professor of Medicine, Harvard Medical School 
Director, Lowe Center for Thoracic Oncology
Director, 
Robert and Renée Belfer Center for Applied Cancer Science
Research Areas: Lung Cancer; Targeted Therapies, Drug Resistance, Preclinical and Clinical Drug Development
Jänne Lab Website
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Rinath Jeselsohn, MD
Assistant Professor of Medicine, Harvard Medical School

Breast Oncology Center
Jeselsohn Lab Website

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William Kaelin, MD
Sidney Farber Professor of Medicine, Harvard Medical School
Nobel Prize Laureate, 2019
Investigator, Howard Hughes Medical Institute
Kaelin Lab Website
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Donald Kufe, MD
Professor of Medicine, Harvard Medical School
Leader, DF/HCC
 Experimental Therapeutics Program
Research Areas: MUC1-C Oncoprotein, Pluripotency, Drug Resistance, Immune Evasion
Kufe Lab Website
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Julie Aurore Losman, MD, PhD
Assistant Professor of Medicine, Harvard Medical School

Research Areas: Acute Myeloid Leukemia; Cancer Cell Metabolism; Epigenetics
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Matthew Meyerson, MD, PhD
Professor of Pathology and Professor of Medicine, Harvard Medical School

​Charles A. Dana Chair in Human Cancer Genetics, Dana-Farber Cancer Institute
Director, Center for Cancer Genome Discovery (CCGD)
Meyerson Lab Website
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Constantine Mitsiades, MD, PhD
Associate Professor of Medicine, Harvard Medical School

Research Areas: Treatment/Immunotherapy Resistance, Tumor Microenvironment, Multiple Myeloma, Solid Tumor Metastasis, Functional Genomics
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Matthew Oser, MD, PhD
Assistant Professor of Medicine, Harvard Medical School
Oser Lab Website
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Kornelia Polyak, MD, PhD
Professor of Medicine, Harvard Medical School
Co-Leader, DF/HCC Cancer Cell Biology Program

Research Areas: Breast Cancer, Tumor Evolution, Heterogeneity, DCIS, Cancer Prevention
Center for Cancer Epigenetics
Polyak Lab Website

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Srivatsan Raghavan, MD, PhD
Instructor in Medicine, Harvard Medical School

Research Areas: Pancreatic and Biliary Cancer, Plasticity and Evolution of cancer cell states, Tumor Microenvironment, Organoid Modeling, Cancer Therapeutics
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Barrett Rollins, MD, PhD
Linde Family Professor of Medicine, Harvard Medical School
Dean for Academic Programs, Dana-Farber Cancer Institute
Research Areas: Histiocytosis, Chemokines
Rollins Lab Website
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William Sellers, MD
Professor of Medicine, Harvard Medical School/DFCI
Core Institute Member, The Broad Institute of MIT and Harvard

Research Areas: Functional Genomics, Cancer Therapeutics
Sellers Lab Website
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​Nilay Sethi, MD, PhD
​Assistant Professor, Harvard Medical School
Associate Director, DF/MGB Hematology/Oncology Fellowship Program
Gastrointestinal Cancer Center
Research Areas: Gastrointestinal Cancer
Sethi Lab Website
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Geoffrey Shapiro, MD, PhD
Professor of Medicine, Harvard Medical School
Senior Vice-President, Drug Development, DFCI

Clinical Director, Center for DNA Damage and Repair
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Ramesh Shivdasani, MD, PhD
Professor of Medicine, Harvard Medical School

Research Areas: Cell Differentiation, Transcriptional Regulation, Stem Cell Biology, Intestinal Stem Cells, Epigenetic Control Mechanisms
Deputy Director, DF/HCC
Shivdasani Lab Website

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Ravi Uppaluri, MD, PhD
Associate Professor of Surgery, Harvard Medical School
Director, Head and Neck Surgical Oncology
Research Areas: Head and Neck Cancers, Immunotherapy, Treatment Resistance

Uppaluri Lab Website

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Srinivas Viswanathan, MD, PhD
​Assistant Professor of Medicine, Harvard Medical School
Research Areas: Genomics, Functional Genomics, Genitourinary Cancer, RNA Binding Proteins
Viswanathan Lab Website
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Nikhil Wagle, MD
Associate Professor of Medicine, Harvard Medical School

Director, Count Me In: Patient-Partnered Research
Wagle Lab Website
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Brian Wolpin, MD, MPH
Professor of Medicine, Harvard Medical School
Director, Gastrointestinal Cancer Center
Co-Director, Pancreas and Biliary Tumor Center
Director, 
Hale Family Research Center
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Molecular and Cellular Oncology Affiliated Investigators
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​Rameen Beroukhim, MD, PhD
Associate Professor of Medicine, Harvard Medical School
Beroukhim Lab Website

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Jennifer L. Guerriero, PhD
Lead Investigator, Brigham and Women’s Hospital
Director, Breast Tumor Immunology Laboratory, Dana-Farber Cancer Institute
Instructor, Harvard Medical School
Guerriero Lab Website
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Alexander Gusev, PhD
Associate Professor of Medicine, Harvard Medical School 
Member, Cancer Genetics and Epigenetics
Member, Cancer Risk, Prevention, and Early Detection


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David Liu, MD, MPH, MS
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Assistant Professor of Medicine, Harvard Medical School



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Elizabeth A. Mittendorf, MD, PhD
Rob and Karen Hale Distinguished Chair in Surgical Oncology
Associate Chair, Research, Department of Surgery Brigham and Women’s Hospital
Director, Breast Immuno-Oncology Program, Dana-Farber/Brigham and Women’s Cancer Center
Professor of Surgery, Harvard Medical School

Mittendorf Lab Website
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Jun Qi, PhD
Assistant Professor of Medicine, Harvard Medical School
Research Areas: Epigenetics, Drug Discovery, Chemical Biology
Qi Lab Website

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©2020 DeCaprio Lab at Dana-Farber Cancer Institute
  • Home
    • Lab News & Highlights
  • Research
    • Merkel cell carcinoma
    • The DREAM complex/Cell cycle
  • People
    • ​James A. DeCaprio, MD
    • Lab Members
    • Alumni
    • Division of Molecular & Cellular Oncology
  • Publications
  • Resources
  • Support Us
  • Contact Us